Patents
Chawla, L. S., McCaffrey, T. A., McPherson, J., & Kampf, M. (2017). Blood biomarkers for appendicitis and diagnostic methods using biomarkers (Publication No. 2017/0356908). December 14, 2017.
Chawla, L. S., & McCaffrey, T. A. (2017). Blood biomarkers for respiratory infections (Publication No. 2017/0369946). December 28, 2017.
Chawla, L. S., & McCaffrey, T. A. (2018). Blood biomarkers for appendicitis and diagnostic methods using biomarkers (Publication No. 2018/0135127). May 17, 2018.
Chawla, L. S., & McCaffrey, T. A. (2021). Blood biomarkers for respiratory infections (Publication No. 2018/006266). March 4, 2021.
Chawla, L. S., & McCaffrey, T. A. (2021). Blood biomarkers for appendicitis and diagnostic methods using biomarkers (U.S. Patent No. 11,066,706). July 20, 2021.
Chawla, L. S., & McCaffrey, T. A. (2022). Blood biomarkers for appendicitis and diagnostic methods using biomarkers (U.S. Patent No. 11,371,096 B2). June 28, 2022.
McCaffrey, T. A., & Chawla, L. S. (2020). Blood biomarkers for respiratory infections (U.S. Patent No. 10,851,418 B2). December 1, 2020.
McCaffrey, T. A., & Chawla, L. S. (2023). Blood biomarkers for respiratory infections (U.S. Patent No. 11,629,383 B2). April 18, 2023.
Journal Articles
Chawla, L. S., Toma, I., Davison, D., Vaziri, K., Lee, J., Lucas, R., Seneff, M. G., Nyhan, A., & McCaffrey, T. A. (2016). Acute appendicitis: Transcript profiling of blood identifies promising biomarkers and potential underlying processes. BMC Medical Genomics, 9, 40. https://doi.org/10.1186/s12920-016-0200-y
Dela Cruz, P., Wargowsky, R., Gonzalez-Almada, A., Sifontes, E. P., Shaykhinurov, E., Jaatinen, K., Jepson, T., LaFleur, J., Yamane, D., Perkins, J., et al. (2024). Blood RNA biomarkers identify bacterial and biofilm coinfections in COVID-19 intensive care patients. Journal of Intensive Care Medicine. Advance online publication. https://doi.org/10.1177/08850666241251743
Jaatinen, K., Shah, P., Mazhari, R., Hayden, Z., Wargowsky, R., Jepson, T., Toma, I., Perkins, J., & McCaffrey, T. A. (2024). RNAseq of INOCA patients identifies innate, invariant, and acquired immune changes: potential autoimmune microvascular dysfunction. Frontiers in Cardiovascular Medicine, 11, 1385457. https://doi.org/10.3389/fcvm.2024.1385457
McCaffrey, T. A., Toma, I., Yang, Z., Katz, R., Reiner, J., Mazhari, R., Shah, P., Tackett, M., Jones, D., Jepson, T., Falk, Z., Wargodsky, R., Shtakalo, D., Antonets, D., Ertle, J., Kim, J. H., Lai, Y., Arslan, Z., Aledort, E., Alfaraidy, M., … St. Laurent, G. (2021). RNA sequencing of blood in coronary artery disease: involvement of regulatory T cell imbalance. BMC Medical Genomics, 14(1), 216. https://doi.org/10.1186/s12920-021-01062-2
Meltzer, A. C., Wargowsky, R. S., Moran, S., Jordan, T., Toma, I., Jepson, T., Shu, S., Ma, Y., & McCaffrey, T. A. (2023). Diagnostic accuracy of novel mRNA blood biomarkers of infection to predict outcomes in emergency department patients with undifferentiated abdominal pain. Scientific Reports, 13, 2297. https://doi.org/10.1038/s41598-023-29385-3
St. Laurent, G., Toma, I., Seilheimer, B., Cesnulevicius, K., Schultz, M., Tackett, M., Zhou, J., Ri, M., Shtokalo, D., Antonets, D., Jepson, T., & McCaffrey, T. A. (2021). RNAseq analysis of treatment-dependent signaling changes during inflammation in a mouse cutaneous wound healing model. BMC Genomics, 22, 854. https://doi.org/10.1186/s12864-021-08083-2
Wargodsky, R., Dela Cruz, P., LaFleur, J., Yamane, D., Kim, J. S., Benjenk, I., Heinz, E., Irondi, O. O., Farrar, K., Toma, I., et al. (2022). RNA sequencing in COVID-19 patients identifies neutrophil activation biomarkers as a promising diagnostic platform for infections. PLOS ONE, 17, e0261679. https://doi.org/10.1371/journal.pone.0261679
Wargowsky, R., Jaatinen, K., Al Munajjed, F., Perkins, J., Meltzer, A., Jepson, T., & McCaffrey, T. (2025). A point-of-care diagnostic platform for detecting host immune activation due to infections: Cytocapture of biomarkers in situ (CyBIS). Journal of Medical Diagnostic Methods, 13, 1–10.