True Bearing Diagnostics

Publications

  1. Publication. 2017/0356908 Blood biomarkers for appendicitis and diagnostic methods using biomarkers. December 14, 2017 (Chawla, McCaffrey, McPherson, & Kampf)
  2. Publication. 2017/0369946. Blood biomarkers for respiratory infections. December 28, 2017 (Chawla & McCaffrey)
  3. Publication. 2018/0135127. Blood biomarkers for appendicitis and diagnostic methods using biomarkers. May 17, 2018 (Chawla & McCaffrey)
  4. Publication 2018/006266. Blood biomarkers for respiratory infections. March 4, 2021 (Chawla & McCaffrey)
  5. Publication. Georges St. Laurent III, Ian Toma, Bernd Seilheimer, Konstantin Cesnulevicius, Myron Schultz, Michael Tackett, Jianhua Zhou, Maxim Ri, Dmitry Shtokalo, Denis Antonets, Tisha Jepson, and Timothy A. McCaffrey, “RNAseq analysis of treatment-dependent signaling changes during inflammation in a mouse cutaneous wound healing model”, BMC Genomics, (2021) 22:854 https://doi.org/10.1186/s12864-021-08083-2 
  6. Publication. Timothy A. McCaffrey, Ian Toma, Zhaoquing Yang, Richard Katz, Jonathan Reiner, Ramesh Mazhari, Palak Shah, Michael Tackett, Dan Jones, Tisha Jepson, Zachary Falk,Richard Wargodsky, Dmitry Shtakalo, Denis Antonets, Justin Ertle, Ju H. Kim, Yinglei Lai, Zeynep Arslan, Emily Aledort, Maha Alfaraidy and Georges St. Laurent III , “RNA sequencing of blood in coronary artery disease: involvement of regulatory T cell imbalance”, BMC Medical Genomics, McCaffrey et al. BMC Med Genomics (2021) 14:216 https://doi.org/10.1186/s12920-021-01062-2
  7. Publication. Jaatinen K, Shah P, Mazhari R, Hayden Z, Wargowsky R, Jepson T, Toma I, Perkins J, McCaffrey TA. “RNAseq of INOCA patients identifies innate, invariant, and acquired immune changes: Potential autoimmune microvascular dysfunction.” Frontiers in Cardiovascular Medicine 2024

Publications Related to TruNav

  1. Chawla LS, Toma I, Davison D, Vaziri K, Lee J, Lucas R, Seneff MG, Nyhan A, McCaffrey TA. Acute appendicitis: transcript profiling of blood identifies promising biomarkers and potential underlying processes. BMC Med Genomics. 2016;9:40. doi: 10.1186/s12920-016-0200-y
  2. Wargodsky R, Dela Cruz P, LaFleur J, Yamane D, Kim JS, Benjenk I, Heinz E, Irondi OO, Farrar K, Toma I, et al. RNA Sequencing in COVID-19 patients identifies neutrophil activation biomarkers as a promising diagnostic platform for infections. PloS one. 2022;17:e0261679. doi: 10.1371/journal.pone.0261679
  3. Meltzer AC, Wargowsky RS, Moran S, Jordan T, Toma I, Jepson T, Shu S, Ma Y, McCaffrey TA. Diagnostic accuracy of novel mRNA blood biomarkers of infection to predict outcomes in emergency department patients with undifferentiated abdominal pain. Scientific Reports. 2023;13:2297. doi: 10.1038/s41598-023-29385-3
  4. Cruz PD, Wargowsky R, Gonzalez-Almada A, Sifontes EP, Shaykhinurov E, Jaatinen K, Jepson T, Lafleur JE, Yamane D, Perkins J, et al. Blood RNA Biomarkers Identify Bacterial and Biofilm Coinfections in COVID-19 Intensive Care Patients. J Intensive Care Med. 2024:8850666241251743. doi: 10.1177/08850666241251743
  5. Wargowsky R, Jaatinen K, Al Munajjed F, Perkins J, Meltzer A, Jepson T, McCaffrey T. A point-of-care diagnostic platform for detecting host immune activation due to infections: Cytocapture of Biomarkers In Situ (CyBIS). Journal of Medical Diagnostic Methods. 2025;13:1-10.